Professor Len Harrison
Immunology Division, Walter & Eliza Hall Institute of Medical Research
"Immunity, like life, is all about regulation"

Our interest is immune mechanisms of disease and immunotherapeutics, in particular the pathogenesis and prevention of diabetes. Diabetes is a major global public and personal health problem. In developed countries, diabetes directly accounts for 10% of health expenditure. We have developed approaches to the pre-clinical diagnosis and prediction of type 1 diabetes and, based on animal model studies, have taken autoantigen-specific vaccination into clinical trials for the prevention of human type 1 diabetes. We now have a major interest in antigen-specific regulatory T cells and in the role of innate immune inflammation in the pathogenesis of insulin resistance and other features of type 2 diabetes.

Theme: Endocrinology and Metabolism
Host: Craig Harrison (PHI)